Alt Title
Gender Differences in tPA Administration
Publication Date
2023
Document Type
Conference Poster
First Advisor
Saravanan, Anitha
Department
School of Nursing
Abstract
As medicine and pharmacology advance through the years, new life-saving treatments are studied or discovered every day, and a medical emergency is no longer a death sentence. Even with conditions as serious as ischemic stroke, there is hope for survival and rehabilitation with the ‘clot-busting’ drug, tissue plasminogen activator, colloquially known as ‘tPA’. tPA is a thrombolytic agent, a substance that acts on fibrin in clots to dissolve them so they can no longer cause ischemia in blood vessels that results in a stroke. (Vega, 2022). tPA is an extremely effective treatment for ischemic stroke, demonstrated in 2013 by a 77% decrease in death from ischemic stroke in America since its approval in 1969 (Vega, 2022). However, not all patients are equally as likely to receive tPA in a manner effective enough for its full therapeutic and life-saving effects to be experienced. Despite women having a higher stroke rate than men on average (Gasbarrino et al, 2022), they are less likely to be triaged correctly or receive rapid administration of tPA for stroke when compared to their male counterparts (Bushnell et al, 2018). Due to this phenomenon, there is speculation on what correlation may exist between gender and quality of ischemic stroke treatment. This research provides in-depth analysis of literature on this subject, finding that both social and biological factors may contribute to reported differences in quality, speed, and efficacy of care between men and women, however, no direct determinants of this disparity have been identified to date.
Recommended Citation
Annerino, Christina, "Gender Differences in Administration of tPA in Treatment of Ischemic Stroke" (2023). CURE Proceedings. 3.
https://huskiecommons.lib.niu.edu/studentengagement-cureposters/3
Publisher
Northern Illinois University
Included in
Community Health and Preventive Medicine Commons, Critical Care Nursing Commons, Geriatric Nursing Commons, Health Services Research Commons, Maternal, Child Health and Neonatal Nursing Commons, Medical Education Commons, Other Pharmacy and Pharmaceutical Sciences Commons, Patient Safety Commons, Perioperative, Operating Room and Surgical Nursing Commons, Pharmacy Administration, Policy and Regulation Commons, Public Health and Community Nursing Commons, Public Health Education and Promotion Commons, Women's Health Commons
Comments
2023 CURE Award Winner - 1st Place in Health and Human Services Posters