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Document Type

Article

Media Type

text

Publication Title

Northern Illinois University Law Review

Abstract

Psychedelics, a class of psychoactive substances that profoundly alter perception, mood, and cognition, show significant promise as a treatment option for mental health conditions such as depression, anxiety, and post-traumatic stress disorder. However, under the current regulatory framework of the Controlled Substances Act, these substances remain classified as Schedule I, the most restrictive category of federal control. This classification has made research and clinical access nearly impossible, largely due to the Drug Enforcement Administration’s insistence on randomized control trial evidence to satisfy the evidentiary standard of “currently accepted medical use” (CAMU). This evidentiary burden reflects more than a veneer of scientific objectivity; it is the product of a drug taboo so powerful that it has locked psychedelic medicine behind layers of stigma, politics, and international control. This Comment argues that the doors of the Schedule I prison have finally begun to crack open. In its recent recommendation to reschedule marijuana, the Department of Health and Human Services introduced a new two-part CAMU test that gives weight to state-authorized treatment programs and the judgment of licensed healthcare providers. This reform offers an unprecedented opportunity for states to generate the evidentiary foundation needed for federal rescheduling. By shifting focus from federal administrative bottlenecks to decentralized state action, this Comment provides a roadmap for legislators, jurists, and advocates to begin the process of rescheduling psychedelic substances, including through the reintroduction of the Illinois Compassionate Use and Research of Entheogens (CURE) Act or comparable legislation.

First Page

245

Last Page

276

Publication Date

Spring 5-1-2026

Department

College of Law

Suggested Citation

Logan P. Doughty, Comment, From Taboo to Treatment: A Trip Through a State-Based Roadmap to Psychedelic Rescheduling, 46 N. Ill. Univ. L. Rev. 245 (2026).

Included in

Law Commons

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