Title

Synthesis and Characterization of Bio-active GFP-P4VP Core–shell Nanoparticles

Authors

Erik Sarnello, Northern Illinois University
Yuzi Liu, Argonne National Laboratory
Bethany Palen, Northern Illinois University
Elaine Sun, Neuqua Valley High School
Xiaobing Zuo, Argonne National Laboratory
Tao Xu, Northern Illinois University
Tao Li, Northern Illinois University

Author ORCID Identifier

Erik Sarnello:https://orcid.org/0000-0001-8357-375X

Bethany Palen:https://orcid.org/0009-0007-4658-1700

Tao Xu:https://orcid.org/0000-0002-3343-7263

Tao Li:https://orcid.org/0000-0002-4913-4486

Publication Title

Catalysts

E-ISSN

43987

Document Type

Article

Abstract

Bioactive core–shell nanoparticles (CSNPs) offer the unique ability for protein/enzyme functionality in non-native environments. For many decades, researchers have sought to develop synthetic materials which mimic the efficiency and catalytic power of bioactive macromolecules such as enzymes and proteins. This research studies a self-assembly method in which functionalized, polymer-core/protein-shell nanoparticles are prepared in mild conditions. Transmission electron microscopy (TEM) and dynamic light scattering (DLS) techniques were utilized to analyze the size and distribution of the CSNPs. The methods outlined in this research demonstrate a mild, green chemistry synthesis route for CSNPs which are highly tunable and allow for enzyme/protein functionality in non-native conditions.

Publication Date

6-1-2020

DOI

10.3390/catal10060627

Keywords

Assembly, Core-Shell Nanoparticle, Immobilization, Polymer, Protein

Recommended Citation

Sarnello, Erik; Liu, Yuzi; Palen, Bethany; Sun, Elaine; Zuo, Xiaobing; Xu, Tao; and Li, Tao, "Synthesis and Characterization of Bio-active GFP-P4VP Core–shell Nanoparticles" (2020). NIU Bibliography. 351.
https://huskiecommons.lib.niu.edu/niubib/351

Department

Department of Chemistry and Biochemistry