Publication Date

2021

Document Type

Dissertation/Thesis

First Advisor

Korampally, Venumadhav

Degree Name

M.S. (Master of Science)

Legacy Department

Department of Electrical Engineering

Abstract

Affordable and easy to use biological assays are the current need of the day owing to the rising cost of health care within the US and worldwide. The goal of this thesis is to develop a sensitive label-free biosensing scheme exploiting surface plasmon resonance (SPR) that yields the sensor output in an easy-to-read optical bio-barcode format for high through put and multiplexed medical diagnostics. Through this research, we would like to investigate if SPR phenomena can be achieved by fabricating SP supporting metallic structures over a nanoporous dielectric layer whose optical constants are progressively varied across the substrate in a bar code format. The optical properties of plasmonic materials are defined by the propagating surface plasmon resonance excited in thin metallic films. The sensor architecture of the proposed biosensor comprises of a metal film (Ag) deposited over a nano porous dielectric layer (NPO); whose refractive indices are gradually varied across the substrate in a bar code format. A fluorescent film is then deposited over the metal. The intensity of the fluorescence emission depends upon the strength of the SPR modes thus producing a bar code of electrical field intensities. The surface plasmon resonance peak position is dependent on the polymer films composition, substrate temperature and silver layer thickness. The proposed sensors can be developed as simple dipsticks and are being intended for use in bed-side diagnostics (commercial applications) and diagnostics for resource poor locations.

Extent

110 pages

Language

eng

Publisher

Northern Illinois University

Rights Statement

In Copyright

Rights Statement 2

NIU theses are protected by copyright. They may be viewed from Huskie Commons for any purpose, but reproduction or distribution in any format is prohibited without the written permission of the authors.

Media Type

Text

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