Author

Jaiweon Hwang

Publication Date

1990

Document Type

Dissertation/Thesis

First Advisor

Kresheck, Gordon C.

Degree Name

M.S. (Master of Science)

Department

Department of Chemistry

LCSH

Phosphine||Phospholipids||Phase partition||Organophosphorus compounds

Abstract

A series of dimethylalkylphosphine oxides containing the octyl, decyl and dodecyl alkyl group were synthesized and characterized according to the procedure of Hays. These compounds behave as nonionic surfactants in an aqueous solution with complex phase diagrams. We have determined the cloud points for several mixtures containing both synthetic and biological phospholipids. Some of the resulting solutions exhibited relative viscosities which were greater than 80% aqueous glycerol indicating the presence of very asymetric mixed micelles as previously reported for micelles containing dimyristoyl phosphatidylcholine and dimethyldecylphosphine oxide. The potential use of these compounds during the isolation of membrane proteins will be discussed.

Comments

Includes bibliographical references (pages [47]-49)

Extent

v, 57 pages

Language

eng

Publisher

Northern Illinois University

Rights Statement

In Copyright

Rights Statement 2

NIU theses are protected by copyright. They may be viewed from Huskie Commons for any purpose, but reproduction or distribution in any format is prohibited without the written permission of the authors.

Media Type

Text

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