Publication Date
1990
Document Type
Dissertation/Thesis
First Advisor
Kresheck, Gordon C.
Degree Name
M.S. (Master of Science)
Legacy Department
Department of Chemistry
LCSH
Phosphine; Phospholipids; Phase partition; Organophosphorus compounds
Abstract
A series of dimethylalkylphosphine oxides containing the octyl, decyl and dodecyl alkyl group were synthesized and characterized according to the procedure of Hays. These compounds behave as nonionic surfactants in an aqueous solution with complex phase diagrams. We have determined the cloud points for several mixtures containing both synthetic and biological phospholipids. Some of the resulting solutions exhibited relative viscosities which were greater than 80% aqueous glycerol indicating the presence of very asymetric mixed micelles as previously reported for micelles containing dimyristoyl phosphatidylcholine and dimethyldecylphosphine oxide. The potential use of these compounds during the isolation of membrane proteins will be discussed.
Recommended Citation
Hwang, Jaiweon, "Phase separation properties of several aqueous alkyl phosphine oxide-phospholipid mixtures" (1990). Graduate Research Theses & Dissertations. 4365.
https://huskiecommons.lib.niu.edu/allgraduate-thesesdissertations/4365
Extent
v, 57 pages
Language
eng
Publisher
Northern Illinois University
Rights Statement
In Copyright
Rights Statement 2
NIU theses are protected by copyright. They may be viewed from Huskie Commons for any purpose, but reproduction or distribution in any format is prohibited without the written permission of the authors.
Media Type
Text
Comments
Includes bibliographical references (pages [47]-49)