Mahiran Basri

Publication Date

1982

Document Type

Dissertation/Thesis

First Advisor

Kresheck, Gordon C.

Degree Name

M.S. (Master of Science)

Legacy Department

Department of Chemistry

LCSH

Micelles; Organophosphorus compounds

Abstract

The characteristics of the mixed micelles formed from various mixtures of dimethyldecylphosphine oxide and dimyristoyl phosphatidylcholine in aqueous solution were studied. The mixed micelles molecular weights were determined from gel filtration studies using Sephadex G-50 and Sephacryl S-200 columns, sedimentation equilibrium studies and sedimentation velocity studies. The cmc for each mole fraction of the mixed micelles were determined from the calorimetric, dye binding and ³¹P NMR studies. The phase diagram was determined from the cloud point studies. The β parameters were calculated using the Sch'eraga-Mendelkern equation using the sedimentation coefficients from the sedimentation velocity experiments and intrinsic viscosities from the viscosity studies. The molecular weights were shown to increase as more DMPC was added. The molecular weight and viscosity studies implied that the shape of the mixed micelles at mole fractions 0.8 and 0.85 is probably ellipsoidal while at mole fraction 0.9 is most probably spherical. The cmc and the cloud points were observed to be decreased as more DMPC was added. Above the cp two distinct insoluble layers were formed upon standing. The top layer consists of DDPO rich mixed micelles and the bottom layer consists of DMPC rich mixed micelles.

Comments

Includes bibliographical references.||Includes illustrations.

Extent

vii, 71 pages

Language

eng

Publisher

Northern Illinois University

Rights Statement

In Copyright

Rights Statement 2

NIU theses are protected by copyright. They may be viewed from Huskie Commons for any purpose, but reproduction or distribution in any format is prohibited without the written permission of the authors.

Media Type

Text

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