Publication Date

4-26-2018

Document Type

Article

First Advisor

Gilbert, Thomas M.

Degree Name

B.S. (Bachelor of Science)

Department

Department of Chemistry and Biochemistry

Abstract

Using 1-hydrosilatrane allows for one-pot direct esterification of aldehydes under mild conditions. This is done by first reducing the aldehyde to an alcohol, and then acetic acid solvent converts the alcohol to the acetate ester. This is unusual, as most reducing agents interact with carboxylic acids to produce side products. Up to 99% conversion of starting aldehyde was observed. The method shows good functional group tolerance, only proving unsuccessful with aldehydes containing strong electron donating groups. A variety of esters were isolated by flash chromatography in yields of 24 – 92%.

Extent

5 pages; 1 poster

Language

eng

Publisher

Northern Illinois University

Rights Statement

In Copyright

Rights Statement 2

NIU theses are protected by copyright. They may be viewed from Huskie Commons for any purpose, but reproduction or distribution in any format is prohibited without the written permission of the authors.

Media Type

Text

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