Jian Zhang

Publication Date


Document Type


First Advisor

Bow, Sing-Tze, 1924-

Degree Name

M.S. (Master of Science)

Legacy Department

Department of Electrical Engineering


Cytoarchitectonics; Cervical vertebrae--Cancer; Cancer--Diagnosis--Equipment and supplies


The goal of this research work is to enhance the cytomorphological deformation in cancer cell detection. Early detection is proved of prime importance in cancer treatment. In the initial stages, cancer can be diagnosed through the detection of the morphological distortion in the exfoliative cell, especially in the nucleus. In particular, accuracy in detecting cervical cancer from the vaginal exfoliated cell is as high as 96%. Therefore, with regular examination and on-time treatment and surgery, death due to cancer of the cervix could be drastically decreased. Color and texture of the cell and their interrelationships are the important bases for cell analyses, and prove successful to differentiate abnormal cells from normal ones. In this thesis, color image processing technique is introduced to highlight the differences between the positive and the pseudo-positive cyto-architectonics so as to help increase the visualization and diagnostic capability of a human expert. Experimental results show that it is effective for the screening of the pseudopositive non-cancerous cells from the cancerous ones even when for some reason they look alike under the microscope.


Includes bibliographical references (pages [86]-89)


ix, 121 pages




Northern Illinois University

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