Wallace, Douglas G.
Ph.D. (Doctor of Philosophy)
Department of Psychology
Neurosciences; Behaviorism (Psychology)
Spatial and temporal processing are critical for an animal's survival. Many neurological disorders are associated with disruptions of these processes. Converging lines of evidence have suggested that these processes are mediated by a cortico-striatal network of structures. Limited research has investigated the role of the medial agranular cortex (AGm) and posterior parietal cortex (PPC) in relation to their overlap in spatial and temporal processing. The current study evaluated the roles of the AGm and PPC in spatial processing and interval timing. Long-Evans rats received unilateral devascularization of either the left hemisphere AGm or PPC followed by testing in the Morris water task (MWT), dark exploration, and food protection. Unilateral damage to these structures was observed to spare performance in all three tasks with a few exceptions. AGm lesion rats were observed to travel longer distances during the first two days of acquisition and demonstrated higher degrees of changes in heading during dark exploration. The selective behavioral disruptions observed in AGm lesion rats may reflect impairments in egocentric-spatial or attentional processing.
Blankenship, Philip A., "The space-time continuum : examining the cortical contributions to spatial and temporal processing" (2018). Graduate Research Theses & Dissertations. 6311.
Northern Illinois University
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