Hess, Edwin A.||Lynch, Darrel L.||Kloss, Robert A.
M.S. (Master of Science)
Department of Biological Sciences
The study was designed to determine the effects of a partially purified thymus extract—thymosin—on lymphopoiesis. Thymosln, reported to be a glycoprotein with a particle weight of 10,000, was injected into immature thymectomized rats. Results showed that an increase in circulating lymphocytes occurred after injection of the thymosin. The increasing lymphocytes resulted from Increased production of the lymphatic system. Evidence supporting this lymphopoietic activity of thymosin was based on increasing weights of the spleen and mesenteric lymph node. Histological investigation noted that these weight changes were the result of increased white pulp of the spleen and increased follicular area of the mesenteric lymph node.
Gillespie, Delmar James, "The effects of a partially purified thymus extract on lymphopoiesis" (1967). Graduate Research Theses & Dissertations. 5598.
Northern Illinois University
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