Mittler, Sidney||Bennett, Jack (Cecil Jackson)
M.S. (Master of Science)
Department of Biological Sciences
The pre-prophase inhibitor urethane was tested for its effect upon ring-shaped X and rod-shaped Y chromosomes in Drosophila melanogaster testes. The XO method was used to detect breakage of the X and Y chromosomes. A successive brood technique showed that the urethane affected greater breakage in the spermatozoa and spermatids in 2000r X-irradiated pre- and post-treated samples. Urethane showed increased breakage in all spermatogenetic cell stages except spermatogonia in non-irradiated samples. Five and seven milligrams of urethane per milliliter of 0.85% NaCl were used as the test concentrations. The control was injected with 0.85% NaCl. Urethane was not shown to affect the production of paternal non-disjunction (XXY) females and mosaics.
Arnesen, James F., "The effect of urethane upon radiation induced genetic change" (1965). Graduate Research Theses & Dissertations. 5582.
vii, 43 pages
Northern Illinois University
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