Mittler, Sidney||Bennett, Jack (Cecil Jackson)
M.S. (Master of Science)
Department of Biological Sciences
The pre-prophase inhibitor urethane was tested for its effect upon ring-shaped X and rod-shaped Y chromosomes in Drosophila melanogaster testes. The XO method was used to detect breakage of the X and Y chromosomes. A successive brood technique showed that the urethane affected greater breakage in the spermatozoa and spermatids in 2000r X-irradiated pre- and post-treated samples. Urethane showed increased breakage in all spermatogenetic cell stages except spermatogonia in non-irradiated samples. Five and seven milligrams of urethane per milliliter of 0.85% NaCl were used as the test concentrations. The control was injected with 0.85% NaCl. Urethane was not shown to affect the production of paternal non-disjunction (XXY) females and mosaics.
Arnesen, James F., "The effect of urethane upon radiation induced genetic change" (1965). Graduate Research Theses & Dissertations. 5582.
vii, 43 pages
Northern Illinois University
Rights Statement 2
NIU theses are protected by copyright. They may be viewed from Huskie Commons for any purpose, but reproduction or distribution in any format is prohibited without the written permission of the authors.