Cassidy, Virginia R.
M.S. (Master of Science)
Department of Nursing
Chest pain; Hemodynamics; Nitroglycerin--Therapeutic use
The differences in absorption of nitroglycerine ointment (NTGO) from four skin sites (outer arm, inner arm, chest, and abdomen) were studied within a physiological framework using the hemodynamic parameter of systolic blood pressure decrease as the dependent variable. A convenience sample of six adult patients admitted to the coronary care unit of an urban university hospital participated in the study. Randomization was accomplished by random assignment of site order with each of the subjects serving as their own control. Blood-pressure measurements were recorded at 15-minute intervals over 24 hours utilizing the Critikon Dinamap®. Analysis of data by MANOVA indicated no significant differences in absorption of nitroglycerine by site (F = .2976, p̲ = .8266). This result was most likely due to the small sample size. The study needs to be repeated utilizing a larger sample before recommendations relating to the most effective site for the application of nitroglycerine ointment can be made.
Hicks, Cherry L., "Hemodynamic changes relative to site of application of nitroglycerine ointment (NTGO) in patients admitted to a coronary care unit with diagnosis of chest pain" (1989). Graduate Research Theses & Dissertations. 3360.
ix, 60 pages
Northern Illinois University
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