Publication Date


Document Type


First Advisor

Schjeide, Ole A.

Degree Name

M.S. (Master of Science)

Legacy Department

Department of Biological Sciences


Liver; X-rays--Physiological effect; Estrogen--Physiological effect


Effects of X-irradiation on protein and lipid synthesis were studied using estrogen-induced synthetic processes of the avian liver as a test model. Female chickens, five weeks old, receiving a single sublethal whole body exposure of 600 R of X-irradiation at a dose rate of 241 R/minute exhibited no significant difference in survival rates or in mean body weights over their non-irradiated hatchmates. The irradiated group did, however, lay significantly fewer and smaller eggs than the non-irradiated group. Determinations of total calcium of yolk, total yolk lipids, and of total non-lipids revealed no differences. Likewise, ultracentri­fuge patterns of yolk were not found to be significantly different. Injection of Estrogenic Substances intramuscularly over a period of three days (12.5 mg, 25 mg, and 12.5 mg on the first, second, and third day respectively) into hens from each group (irradiated and non-irradiated) resulted in greater enlargement in control estrogenized birds than in livers of irradiated estrogenized birds (p < .05). Weights of control and irradiated livers receiving no estrogen were not significantly different. Furthermore, no differences were ascertained to exist between control and irradiated birds in ratios of RNA to DNA or amounts of lipid and non­lipid solids when comparisons were made between equal volumes of their livers. No significant differences were detected in the calcium content in the serums from control and irradiated hens. Further, no differences were seen in the serum content of either total lipid or total non-lipid solids.


Includes bibliographical references.||Includes illustrations.


viii, 62 pages




Northern Illinois University

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