Publication Date


Document Type


First Advisor

Oddi, Lorys

Degree Name

M.S. (Master of Science)

Legacy Department

School of Nursing


Catheters--Sanitation; Microbial contamination; Catheterization--Complications


The optimal frequency for changing flush solution, as part of the pressuremonitoring system for arterial catheters, has not yet been determined. Contamination of the flush solution is a concern, as it can contribute to a nosocomial bloodstream infection. The purpose of this study was to compare the contamination rates between nurse-prepared flush solutions at three change time intervals. Seventy adult, critically ill patients provided the sample for the study. In Group A (n?=19), the control group, a 24-hour interval between changes of flush solution was used, according to the policy of the study hospital. In Group B (n?=31), a 48-hour interval between changes was used, while in Group C (n?=20), a 72-hour interval between changes was used. No significant difference regarding contamination of flush solution was found between groups (F? = 1.60, p? = .2087). These findings suggest that changing nurse-prepared flush solution every 48 or 72 hours presents no greater risk of a bloodstream infection than changing flush solution every 24 hours.


Includes bibliographical references (pages [40]-42)


vi, 70 pages




Northern Illinois University

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