Publication Date


Document Type


First Advisor

Johnson, Rebecca A. (Rebecca Ann)

Degree Name

M.S. (Master of Science)

Legacy Department

Department of Nursing


Cardiovascular system--Surgery; Respiratory agents; Analgesia


Analgesia is commonly withheld from cardiovascular surgical patients soon to be withdrawn from mechanical ventilation to prevent respiratory depression that can postpone extubation. The effects o f analgesia on respiration have been inadequately studied. In this study, weaning parameter measurements were obtained to determine the respiratory impact o f a low dose o f intravenous morphine in cardiovascular surgical patients ready to be weaned from the ventilator. A pretest-posttest, quasi-experimental, repeated measures design was used. The conceptual model consisted o f the physiology o f respiration and intrinsic and extrinsic factors affecting respiration. Eleven alert subjects who met two o f five weaning parameter criteria received 1 to 5 mg o f morphine. Weaning parameters were measured before the intervention and 15 and 30 minutes afterward. Using an alpha level o f 0.05, dependent paired t tests were calculated to detect changes due to the morphine. As hypothesized, low dose morphine administration was not found to negatively influence weaning parameters.


Includes bibliographical references (pages [66]-69)


viii, 100 pages




Northern Illinois University

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